BDBM14153 2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benzodiazol-2-yl}-6-phenylbenzen-1-olate::APC-10762

SMILES NC(=[NH2+])c1cc2[nH]c(nc2cc1Cl)-c1cccc(-c2ccccc2)c1[O-]

InChI Key InChIKey=RPGVMAPDADAHPV-UHFFFAOYSA-N

Data  23 KI

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14153   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14153(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benz...)
Affinity DataKi:  810nM ΔG°:  -8.22kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14153(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benz...)
Affinity DataKi:  2.10E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14153(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benz...)
Affinity DataKi:  3.30E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14153(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benz...)
Affinity DataKi:  4.20E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14153(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benz...)
Affinity DataKi:  4.20E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair